Different mutations can have different effects on brain cell activity
Different mutations that cause Rett syndrome can have divergent effects on brain cell activity, a study found.
The findings “hold promise for understanding mutation-specific mechanisms of Rett syndrome, and developing targeted mutation-specific therapeutics,” the researchers wrote.
Through a series of experiments using cell models, the researchers identified biochemical strategies to normalize brain cell activity in people with Rett caused by specific mutations… Continue reading.